Method of using cyclooxygenase-2 inhibitors in the treatment...

Details Method of using cyclooxygenase-2 inhibitors in the treatment... Method of using cyclooxygenase-2 inhibitors in the treatment...

A - Human Necessities

61

K

A61K 31/415 (2006.01) A61K 31/10 (2006.01) A61K 31/18 (2006.01) A61K 31/4155 (2006.01) A61K 31/4164 (2006.01) A61K 31/4178 (2006.01) A61K 31/42 (2006.01) A61K 31/421 (2006.01) A61K 31/426 (2006.01) A61K 31/4418 (2006.01) A61K 31/4439 (2006.01) A61K 31/635 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2267186

This invention relates to the use of cyclooxygenase-2 inhibitors or derivatives thereof in preventing and treating neoplasia. In particular, the invention describes the method of preventing and heating epithelial cell neoplasia in a subject, said method comprising seating the subject with a therapeutically-effective amount of a compound of Formula (I) wherein A, R2 and R3 are as described in the specification.

Cette invention a trait à l'application d'inhibiteurs de la cyclogénase-2 ou de ses dérivés au traitement et à la prévention du processus néoplasique. Elle décrit notamment la technique de prévention et de traitement du processus néoplasique de la cellule épithéliale chez un sujet. Cette technique consiste à traiter le sujet avec une quantité efficace du point de vue thérapeutique d'un composé de la formule (I) dans laquelle A, R<2> et R<3> sont tels que décrits dans l'énoncé de l'invention.

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