Method of using cyclooxygenase-2 inhibitors in the treatment...

A - Human Necessities – 61 – K

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A61K 31/635 (2006.01) A61K 31/415 (2006.01)

Patent

CA 2285434

This invention relates to the use of cyclooxygenase-2 inhibitors or derivatives thereof in preventing and treating dementia. In particular, the invention describes the method of preventing and treating dementia in a subject, said method comprising treating the subject with a therapeutically- effective amount of a compound of formula (I) wherein R2, R3, and R4 are as described in the specification.

La présente invention concerne un procédé se rapportant à l'utilisation d'inhibiteurs de la cyclo-oxygénase-2, ou de certains de leurs dérivés, pour la prévention et le traitement de la démence. L'invention porte plus particulièrement sur une technique de traitement et de prévention de la démence chez un sujet, lequel procédé consiste à traiter le sujet en lui administrant une quantité thérapeutiquement suffisante d'un composé représenté par la formule générale (I), pour R?2¿, R?3¿ et R?4¿ tels que spécifiés par les revendications de la demande.

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