Method of using pore-forming peptides for genetic...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/87 (2006.01) C07K 7/00 (2006.01) C07K 14/00 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 15/00 (2006.01) C12N 15/63 (2006.01)

Patent

CA 2620935

There are currently few effective approaches for the non-specific transport of molecules across cell membranes. The present application discloses methods of introducing molecules into and extracting molecules out of a cell in a non- specific manner using antimicrobial peptides. Further, the application discloses methods of utilizing antimicrobial peptides to enhance the competence of bacterial cells that have been rendered competent for genetic transformation.

There are currently few effective approaches for the non-specific transport of molecules across cell membranes. The present application discloses methods of introducing molecules into and extracting molecules out of a cell in a non-specific manner using antimicrobial peptides. Further, the application discloses methods of utilizing antimicrobial peptides to enhance the competence of bacterial cells that have been rendered competent for genetic transformation.

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