Method of using substituted piperidines that increase p53...

A - Human Necessities – 61 – K

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Details

A61K 31/45 (2006.01) A61K 31/454 (2006.01) A61K 31/4545 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2656393

The present invention discloses a method of using compounds, which have HDM2 protein antagonist activity, to treat or prevent cancer, other diseases caused by abnormal cell proliferation, diseases associated with HDM2, or diseases caused by inadequate P53 activity.

La présente invention concerne un procédé d'utilisation de composés dotés d'une activité antagoniste vis-à-vis de la protéine HDM2 en vue de traiter ou de prévenir un cancer, d'autres maladies causées par une prolifération cellulaire anormale, des maladies associées à HDM2, ou des maladies induites par une activité de P53 inadéquate.

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