Method, system, and software for analyzing pharmacovigilance...

G - Physics – 06 – F

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G06F 19/00 (2011.01) G06F 17/18 (2006.01)

Patent

CA 2585269

A computer-implemented method of analyzing a dataset of pharmacovigilance data, includes determining a sample size-independent measure of association between two conditions of interest in the dataset of pharmacovigilance data; using a hypergeometric distribution to determine a measure of statistical unexpectedness between the conditions of interest in said dataset, wherein the distribution is based on an urn model under a hypothesis that the conditions are statistically independent; and displaying the measure of association with the measure of the statistical unexpectedness to identify a significant association between conditions of interest.

L'invention concerne un procédé à mise en oeuvre informatique, d'analyse d'un ensemble de données de pharmacovigilance, procédé comprenant les étapes suivantes : détermination d'une mesure, indépendante de la taille d'un échantillon, d'association entre deux conditions à considérer dans l'ensemble de données de pharmacovigilance ; utilisation d'une distribution hypergéométrique pour déterminer une mesure d'imprévisibilité statistique entre les conditions à considérer dans ledit ensemble de données, la distribution étant basée sur un modèle en urne dans l'hypothèse où les conditions sont statistiquement indépendantes ; et affichage de la mesure d'association avec la mesure d'imprévisibilité statistique afin d'identifier une association significative entre les conditions considérées.

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