Method to detect biologically active, allergen-specific...

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G01N 33/68 (2006.01) C07K 14/735 (2006.01) C07K 16/00 (2006.01)

Patent

CA 2328079

The present invention includes a method to detect a biologically active, allergen-specific immunoglobulin using a Fc epsilon receptor (Fc.epsilon.R) molecule. Such a method can detect biologically active, allergen-specific immunoglobulins not detectable by a process using anti-IgE antibodies. The present invention also relates to kits to perform such methods. The present invention also includes a heat stable, biologically active, allergen-specific immunoglobulin.

La présente invention concerne un procédé de détection d'une immunoglobuline spécifique aux allergènes, biologiquement active, à l'aide d'une molécule réceptrice Fc epsilon (Fc¿.epsilon.?R). Cette méthode permet la détection d'immunoglobulines spécifiques aux allergènes, biologiquement actives, qui ne sont pas détectables avec un procédé qui utilise des anticorps anti-IgE. La présente invention concerne aussi un nécessaire destiné à mettre en oeuvre de telles méthodes, et une immunoglobuline spécifique aux allergènes, biologiquement active et thermostable.

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