Method to determine a predisposition to leptin treatment

G - Physics – 01 – N

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G01N 33/74 (2006.01) C07K 14/575 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2344623

Low baseline serum leptin levels are used to forecast whether or to what degree an individual may be responsive to leptin administration. Methods and related compositions are disclosed, based on a determination of whether an individual has a baseline serum leptin level in approximately the bottom 25 % of a selected obese population.

On utilise de faibles taux sériques de leptine de base, afin de prévoir si un individu peut être sensible à la leptine et à quel degré. L'invention concerne des procédés et des compositions permettant de déterminer si un individu présente un taux sérique de leptine de base se trouvant dans environ le quart inférieur d'une population sélectionnée d'obèses.

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