Method to determine the differentiation potential of a...

Details Method to determine the differentiation potential of a... Method to determine the differentiation potential of a...

C - Chemistry, Metallurgy

12

Q

C12Q 1/02 (2006.01) C12N 5/0735 (2010.01) A61K 35/54 (2006.01) A61K 35/12 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2410684

The present invention relates to a method to determine the differentiation potential of a target cell, said method comprising exposing the target cell ex utero to an early embryonic environment and detecting the progeny of said target cell. The invention further relates to the use of these methods to identify or provide cells for therapy or prophylaxis and the use of said cells in the manufacture of a medicament for use in therapy or prophylaxis.

La présente invention concerne un procédé visant à évaluer le potentiel de différentiation d'une cellule cible. A cet effet, on expose la cellule cible hors utérus à un environnement embryonnaire précoce, puis on détecte la descendance de ladite cellule cible. L'invention concerne également, d'une part l'utilisation de ce procédé pour identifier ou fournir des cellules à des fins de thérapie ou de prophylaxie, et d'autre part l'utilisation de ces cellules pour la fabrication d'un médicament convenant à des fins de thérapie ou de prophylaxie.

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