Method to enhance hematopoiesis

Details Method to enhance hematopoiesis Method to enhance hematopoiesis

A - Human Necessities

61

K

A61K 38/00 (2006.01) A61K 38/19 (2006.01)

Patent

CA 2538422

The present invention relates generally to the fields of immunology and molecular biology, and particularly to a method for treating hematopoietic disorders. The invention provides a method to treat a deficiency of one or more types of blood cells in a mammal, which includes administering an effective amount of TISF or of a compound that stimulates CD4+ cells like TISF does. In one embodiment, TISF that originates from a mammalian species is administered to a mammalian subject diagnosed as having a deficiency in one or more types of blood cells.

La présente invention concerne généralement les domaines de l'immunologie et de la biologie moléculaire, et en particulier un procédé de traitement des troubles hématopoïétiques. L'invention porte sur un procédé qui permet de traiter une déficience d'un ou plusieurs types de cellules sanguines chez un mammifère, lequel procédé consiste à administrer une quantité efficace d'un facteur de stimulation immune de lymphocytes T4 (TISF) ou d'un composé qui, à l'instar du TISF, stimule les cellules CD4+. Dans un mode de réalisation, on administre un TISF issu d'une espèce mammalienne à un sujet mammalien que l'on a diagnostiqué comme souffrant d'une déficience d'un ou plusieurs types de cellules sanguines.

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