Method to enhance osteoblast functionality and measure...

A - Human Necessities – 61 – L

Patent

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Details

A61L 27/50 (2006.01) G01N 27/00 (2006.01)

Patent

CA 2694518

A method to enhance osteoblast functionality of a medical implant. The method may include obtaining the medical implant and treating a surface of the medical implant to modify the surface characteristics causing increase functionality of adjacent positioned osteoblasts. A method of increasing cellular activity of a medical implant is also disclosed. A medical device having enhanced cytocompatibility capabilities includes a metallic substrate with an outer surface. Attached to the outer surface is a composition of nanosized structures. A biosensor for use with a medical device, includes an electrode that is attached to an outer surface of the medical device. The biosensor measures electrochemical changes adjacent to the medical implant. Further, a method of manufacturing a medical implant with a biosensor for use in vivo and a method of integrating a biosensor with a medical implant for use in monitoring conductivity and electrochemical changes adjacent to the medical implant are disclosed.

La présente invention concerne un procédé permettant d'accroître la fonction ostéoblastique d'un implant médical. L'invention porte aussi sur l'obtention d'un implant médical et le traitement d'une surface de l'implant médical afin de modifier les caractéristiques de la surface en vue d'accroître la fonction des ostéoblastes adjacents. De plus, l'invention a trait à un procédé permettant d'accroître l'activité cellulaire d'un implant médical. Un dispositif médical présentant des capacités accrues de cytocompatibilité comprend un substrat métallique doté d'une surface externe. Une composition de structures nanométriques est fixée sur la surface externe. Un biocapteur, qui s'utilise avec un dispositif médical, comprend une électrode fixée à une surface externe du dispositif médical. Le biocapteur mesure les modifications électrochimiques adjacentes à l'implant médical. En outre, l'invention se rapporte à un procédé de fabrication d'un implant médical équipé d'un biocapteur à utiliser in vivo et un procédé permettant d'incorporer un biocapteur à un implant médical à utiliser lors du suivi de la conductivité et des changements électrochimiques adjacents à l'implant médical.

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