Method to generate correlative data from various products of...

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G01R 19/00 (2006.01) C12M 1/34 (2006.01) G01N 31/12 (2006.01) G01R 19/165 (2006.01) G01R 19/25 (2006.01) H01J 49/04 (2006.01)

Patent

CA 1082311

A B S T R A C T In a method generating correlative data from various products of thermal degradation of biological specimens and comprising sequential steps for each specimen of degrading such specimen by heating such specimen so as to cause various products of thermal degradation of such specimen to be evolved, ionizing the products of thermal degradation of such specimen by a technique causing negligible fragmentation, detecting ion currents for such specimen, and record- ing such detected ion currents, an improvement is attained wherein each specimen is heated in an identical nonisothermal time-dependent healing sequence, wherein a three-dimensional array comprising a large and suffi- cient number of ion currents, which correspond to substantially all detectible ratios of mass-to-charge within a range at a large and sufficient number of successive instants during the respective healing sequences, are detected and recorded for each specimen, and representative data from the three-dimensional array thus recorded for each one of such specimens are correlated to representative data from the three-dimensional array thus recorded for each other of the specimens. Therein, one dimension of each array represents ion currents, another dimension of such array represents mass- to-charge ratios, and another dimension of such array represents specimen temperatures.

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