Methodology for the immuno-diagnosis of multiple sclerosis...

Details Methodology for the immuno-diagnosis of multiple sclerosis... Methodology for the immuno-diagnosis of multiple sclerosis...

C - Chemistry, Metallurgy

12

Q

167/45

C12Q 1/00 (2006.01) G01N 33/54 (1980.01)

Patent

CA 1164798

ABSTRACT OF THE DISCLOSURE New and improved methodology for the diagnosis of a dis- ease from blood sample analysis is disclosed and comprises: the preparation of a putative antigenic body substance ex- tract, which is specific to disease-sensitized blood leuko- cytes, from the pooled, like body substances of a plurality of donors known to have the disease of interest; the mixture of said extract with the blood sample leukocytes; the promo- tion of the reaction therebetween to modify a characteristic of the disease-sensitized leukocytes, if any, to which said characteristic has been modified. In multiple sclerosis diagnosis, said body substance may be blood or urine; while for malignant disease (for example breast cancer, or cancer of the head and neck) said body substance may be blood, urine, pleural fluid, ascites fluid, supernates of tumor cell cul- tures or tumor cells grown in culture media.

366087

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