C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/70 (2006.01) C12N 15/63 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2574076
The invention relates to the fields of screening assays, compounds, and methods for altering gene expression and protein levels. In particular, the invention includes assays to screen for agents capable of modulating gene expression in a UTR-dependent manner and agents capable of modulating gene expression.
La présente invention a pour objet des opérations de criblage, des composés criblés ou à cribler, ainsi que des méthodes de criblage permettant l~identification de composés actifs dans le domaine de l~altération de l~expression d~un gène et des taux de protéines. Dans un mode préféré de l~invention, cette dernière a pour objet les opérations de criblage visant à identifier des agents capables de moduler l~expression d~un gène en fonction des séquences non traduites (UTR), ainsi que lesdits agents.
Cao Liangxian
Mehta Anuradha
Naryshkin Nikolai A.
Pelligrini Matthew C.
Romfo Charles M.
Osler Hoskin & Harcourt Llp
Ptc Therapeutics Inc.
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