G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 27/447 (2006.01) B01J 19/00 (2006.01) C07K 1/12 (2006.01) G01N 27/30 (2006.01) G01N 27/44 (2006.01) G01N 31/00 (2006.01) G01N 33/68 (2006.01) G01N 30/06 (2006.01)
Patent
CA 2079005
2079005 9115758 PCTABS00007 A first reactant is immobilized i.e. in a porous matrix (50), adjacent a sample electrode (46) within a reaction chamber. Energizing of the electrode (46) electrophoretically attracts a mobile second reactant and/or electrolytically induces appropriate reaction conditions to enhance reaction of the first and second reactants. Polarity reversals between the sample electrode (46) and remote electrodes (38, 42, 44) cause unreacted second reactant and/or by-products to migrate away from the immobilized first reactant. The techniques are useful for sequential chemical reactions such as sequencing or construction of proteins, polysaccharides and nucleic acids where cyclical additions and removals of reactants are required. The techniques are amenable to automated micro and nano scale construction and operation and allow direct electrophoretic (38) interfacing with chromatographic, HPCE and mass spectrophotometric equipment.
Begg Geoffrey Stephen
Burgess Antony Wilks
Simpson Richard John
Fetherstonhaugh & Co.
Ludwig Institute For Cancer Research
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