Methods and apparatus for blood typing with optical bio-discs

Details Methods and apparatus for blood typing with optical bio-discs Methods and apparatus for blood typing with optical bio-discs

G - Physics

01

N

G01N 33/567 (2006.01) G01N 33/80 (2006.01)

Patent

CA 2467740

This invention relates to clinical diagnostic assays, related optical bio- discs, and a disc-reading apparatus. The invention is directed to methods and apparatuses for performing immunohematology assays using an optical bio-disc analysis system. The invention is further directed to an optical bio-disc for performing an immunohematologic assay including a substrate having encoded information associated therewith. The encoded information may be readable by a disc drive assembly to control rotation of the disc. The disc may also include at least one target zone or capture zone associated with the substrate. The target zone is disposed at a predetermined location relative to a center of the substrate. The disc further includes a capture antibodies immobilized within the target zone, a flow channel, fluidic circuit, or analysis chamber associated with the target zone, and an input site in fluid communication with the analysis chamber.

L'invention concerne des analyses diagnostiques cliniques, des bio-disques optiques associés et un appareil de lecture de bio-disque. L'invention concerne également des méthodes et des appareils servant à exécuter des analyses d'immunohématologie à l'aide d'un système d'analyse de bio-disques optiques. L'invention concerne, de plus, un bio-disque optique servant à effectuer une analyse immunohématologique comprenant un substrat avec des informations codées associées. Les informations codées peuvent être lues par un ensemble d'entraînement de disques afin de commander la rotation du disque. Le disque peut également comprendre au moins une zone cible ou zone de capture associée au substrat. La zone cible est disposée à un emplacement prédéterminé par rapport au centre du substrat. Le disque comprend également une pluralité d'anticorps de capture immobilisés dans la zone cible, un canal d'écoulement, un circuit fluidique, ou une chambre d'analyse associée à la zone cible, et un site d'entrée en communication fluidique avec la chambre d'analyse.

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