Methods and apparatus for isotopic analysis

G - Physics – 01 – N

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G01N 21/39 (2006.01) G01N 21/62 (2006.01) G01N 27/62 (2006.01) G01N 33/497 (2006.01) G01N 33/60 (2006.01) G01N 21/68 (2006.01) A61K 49/02 (1990.01)

Patent

CA 2088100

The isotopic composition of a multiatomic isotope-bearing species such as CO2 in an analyte is measured by maintaining the analyte in a condition such that isotope-bearing species are present in an excited state and directing light at wavelengths corresponding to transition energies of isotope-bearing species with different isotopes. The interaction between the analyte and light at the different wavelengths is monitored, as by monitoring the optogalvanic effect caused by the light of the different wavelengths. The light may be supplied by a laser including the isotope-bearing species. A stable isotope such as 13C or 18O can be used as a tracer in a chemical or biological test and detected using the composition-determining method.

La composition isotopique d'un échantillon multiatomique contenant des isotopes, tel que du CO2, dans une substance à analyser se mesure en maintenant ladite substance dans une condition telle que l'échantillon contenant les isotopes se trouve dans un état excité, et en l'irradiant avec de la lumière à des longueurs d'onde correspondant aux énergies de transition des échantillons à isotopes différents. L'interaction entre la substance à analyser et la lumière aux différentes longueurs d'onde est contrôlée en surveillant l'effet octogalvanique causé par la lumière à ces différentes longueurs d'onde. Cette lumière peut être fournie par un laser comportant l'échantillon contenant les isotopes. Un isotope stable tel que 13C ou 18O peut être utilisé comme traceur dans un test chimique ou biologique et être détecté au moyen de la méthode d'analyse des substances.

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