Methods and apparatus for making liposomes using critical,...

A - Human Necessities – 61 – K

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A61K 9/127 (2006.01) A61K 38/00 (2006.01) B01J 13/02 (2006.01)

Patent

CA 2163903

The present application features methods and apparatus for making lipsomes with critical, supercritical or near critical fluids. The methods and apparatus combine a phospholipid and an aqeuous phase, or multilamellar vesicles, with a critical, supercritical or near critical fluid. Upon a reduction in pressure, liposomes are formed.

La présente invention se rapporte à des procédés et à un appareil destinés à la production de liposomes à l'aide de fluides critiques, supercritiques ou presque critiques. Ces procédés et cet appareil permettent de combiner un phospholipide et une phase aqueuse, ou des vésicules multilamellaires, avec un fluide critique, supercritique ou presque critique. Des liposomes sont formés lorsque la pression est réduite.

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