Methods and apparatus for modifying properties of the bbb...

A - Human Necessities – 61 – B

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A61B 17/00 (2006.01) A61B 19/00 (2006.01) A61K 9/12 (2006.01) A61K 45/00 (2006.01) A61M 31/00 (2006.01)

Patent

CA 2483635

A method for modifying a property of a brain of a patient includespresenting an odorant to an air passage of the patient, the odorant havingbeen selected for presentation to the air passage because it is such as toincrease conductance of molecules from a systemic blood circulation of thepatient through a blood brain barrier (BBB) of the brain into brain tissueof the patient. The molecules are selected from the group consisting of: apharmacological agent, a therapeutic agent, an endogenous agent, and anagent for facilitating a diagnostic procedure.

L'invention concerne une méthode permettant de modifier une propriété cérébrale d'un patient qui consiste à présenter un agent odorant dans un passage aérien dudit patient, ledit agent odorant ayant été sélectionné pour être présenté dans le passage aérien afin d'augmenter la conductance de molécules de la circulation sanguine systémique du patient à travers la barrière hémato-encéphalique (BBB) du cerveau dans le tissu cérébral de ce patient. Les molécules sont sélectionnées dans le groupe constitué par un agent apharmacologique, un agent thérapeutique, un agent endogène et un anagent afin de faciliter une procédure de diagnostic.

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