Methods and apparatus for segregation of particles

Details Methods and apparatus for segregation of particles Methods and apparatus for segregation of particles

C - Chemistry, Metallurgy

12

Q

C12Q 1/24 (2006.01) G01N 33/49 (2006.01)

Patent

CA 2722396

The disclosure relates to an apparatus for segregating particles on the basis of their ability to flow through a stepped passageway. At least some of the particles are accommodated in a passage bounded by a first step, but at least some of the particles are unable to pass through a narrower passage bounded by a second step, resulting in segregation of the particles. The apparatus and methods described herein can be used to segregate particles of a wide variety of types. By way of example, they can be used to segregate fetal-like cells from a maternal blood sample.

L'invention concerne un appareil de ségrégation de particules en fonction de leur capacité à s'écouler dans un passage à gradins. Au moins certaines des particules sont accueillies dans un passage borné par un premier gradin, mais au moins certaines particules sont incapables de passer dans un passage plus étroit borné par un second gradin, ce qui permet la ségrégation des particules. L'appareil et les procédés décrits peuvent être utilisés pour ségréguer des particules de types très divers. A titre d'exemple, ils peuvent être utilisés pour ségréguer des cellules de type ftal dans un échantillon de sang maternel.

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