Methods and apparatus for separation of blood components

Details Methods and apparatus for separation of blood components Methods and apparatus for separation of blood components

A - Human Necessities

61

K

A61K 35/14 (2006.01) A61M 1/36 (2006.01) B04B 5/04 (2006.01) G01N 33/49 (2006.01) G01N 33/50 (2006.01) A61M 1/02 (2006.01)

Patent

CA 2455964

The present invention is directed to a method and system that separates first particles from second particles, or white blood cells from red blood cells, by sedimentation in a fluid chamber with debulking of one of the first or second particles or red blood cells through the inlet of the fluid chamber. The method and system further includes fractionation of the remaining particles or white blood cells into selected subsets. In one embodiment of the instant invention a blood product containing white blood cells is loaded in a separation chamber, a diluting or sedimenting agent is added to encourage rouleaux formation of any red blood cells, the cells are sedimented and the red blood cells are removed.

La présente invention concerne un procédé et un système pour séparer des premières particules de secondes particules, ou des leucocytes sanguins de globules rouges sanguins, par sédimentation dans un compartiment à liquide avec réduction de volume des premières ou des secondes particules, ou des globules rouges sanguins par l'entrée du compartiment à liquide. Le procédé et le système comprennent également le fractionnement des particules restantes ou des leucocytes sanguins, en sous-ensembles sélectionnés. Dans un mode de réalisation de l'invention, un produit sanguin contenant des leucocytes sanguins est introduit dans un compartiment de séparation, un agent de dilution ou de sédimentation est ajouté pour favoriser la formation de rouleaux de tous les globules rouges sanguins, les cellules sont sédimentées et les globules rouges sanguins éliminés.

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