Methods and apparatus for stenting comprising enhanced...

A - Human Necessities – 61 – F

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A61F 2/06 (2006.01)

Patent

CA 2401878

Apparatus and methods for stenting are provided comprising a stent attached to a porous biocompatible material that is permeable to endothelial cell ingrowth, but impermeable to release of emboli of predetermined size. Preferred stent designs are provided, as well as preferred manufacturing techniques. Apparatus and methods are also provided for use at a vessel branching. Moreover, embodiments of the present invention may comprise a coating configured for localized delivery of therapeutic agents. Embodiments of the present invention are expected to provide enhanced embolic protection, improved force distribution, and improved recrossability, while reducing a risk of restenosis and thrombus formation.

L'invention concerne des dispositifs et des procédés permettant d'assurer une protection au moyen d'un extenseur et consistant en un extenseur fixé à un matériau biocompatible poreux perméable à la croissance cellulaire endothéliale mais imperméable à la libération de caillots de dimension prédéterminée susceptibles de provoquer une embolie. Elle concerne des conceptions préférées d'extenseur, ainsi que des techniques préférées de fabrication. Elle concerne également des dispositifs et des procédés conçus pour être mis en application au niveau de la ramification d'un vaisseau. De plus, des modes de réalisation peuvent comprendre un revêtement conçu pour administrer localement des agents thérapeutiques. Certains modes de réalisation peuvent permettre d'améliorer la protection contre les embolies, la répartition des forces et les recroisements, tout en limitant le risque de resténose et de formation de thrombus.

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