Methods and apparatus for treatment of parkinson's disease

Details Methods and apparatus for treatment of parkinson's disease Methods and apparatus for treatment of parkinson's disease

A - Human Necessities

61

K

A61K 9/70 (2006.01) A61K 31/19 (2006.01) A61K 31/198 (2006.01) A61K 31/216 (2006.01) A61K 47/10 (2006.01) A61K 47/12 (2006.01)

Patent

CA 2268455

A pharmaceutical composition for treatment of Parkinson's disease comprising a compound of levodopa dissolved in a non-degradative solvent which allows transdermal administration of levodopa. The compound of levodopa is an alkyl-ester of levodopa and the solvent is a formulation comprising a substantially non-aqueous solvent, a transdermal enhancer and a detergent. The alkyl-ester of levodopa is preferably levodopa-ethyl-ester (LDEE).

Une composition pharmaceutique de traitement de la maladie de Parkinson comprend un composé de lévodopa dissous dans un solvant non dégradant permettant l'administration transdermique de lévodopa. Le composé de lévodopa est un alkyl-ester de lévodopa et le solvant est une formulation comprenant un solvant sensiblement non aqueux, un activateur transdermique et un détergent. L'alkyl-ester de lévodopa est de préférence un lévodopa-éthyl-ester (LDEE).

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