G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/487 (2006.01) G01N 21/25 (2006.01) G01N 21/47 (2006.01) G01N 21/64 (2006.01) G01N 33/542 (2006.01) G01N 33/68 (2006.01) G01N 15/02 (2006.01)
Patent
CA 2477021
The invention provides methods and apparatuses for characterizing the folding and aggregation dynamics of biological molecules, including stability of biological molecules. The methods and apparatuses of the invention can be used, for example, to identify conditions that affect the stability of a biological molecule, to identify compounds or ligands that bind to a biological molecule, and to identify compounds that modulate the interaction between a biological molecule and a ligand.
L'invention concerne des méthodes et des dispositifs destinés à caractériser la dynamique de repliement et d'agrégation de molécules biologiques, et notamment la stabilité de molécules biologiques. Les méthodes et les dispositifs de l'invention peuvent être utilisés, par exemple, pour identifier des états pathologiques affectant la stabilité d'une molécule biologique, pour identifier des composés ou des ligands se liant à une molécule biologique, et pour identifier des composés modulant l'interaction entre une molécule biologique et un ligand.
Hui Raymond
Markin Eugene
Senisterra Guillermo
Yamazaki Ken
Affinium Pharmaceuticals Inc.
Bereskin & Parr
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