C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/00 (2006.01) C12M 1/00 (2006.01) C12M 1/36 (2006.01) C12M 1/38 (2006.01) C12N 11/00 (2006.01) C12Q 1/02 (2006.01) C12Q 1/18 (2006.01) C12Q 1/68 (2006.01) G01N 33/00 (2006.01) G01N 33/53 (2006.01) G01N 33/567 (2006.01)
Patent
CA 2643993
Arrays of single molecules and methods of producing an array of single molecules are described. Arrays with defined volumes between 10 attoliters and 50 picoliters enable single molecule detection and quantitation. Biomolecules such as enzymes can be addressed at the single molecule level in order to discover function, detect binding partners or inhibitors, and/or measure rate constants.
L'invention concerne des réseaux de molécules uniques ainsi que des procédés de production de réseaux de molécules uniques. Des réseaux ayant des volumes définis, allant de 10 attolitres à 50 picolitres, permettent la détection et la quantification de molécules uniques. Des biomolécules telles que des enzymes peuvent être examinées au niveau de la molécule unique afin d'en découvrir la fonction, de détecter des partenaires ou des inhibiteurs de liaison et/ou de mesurer des constantes de vitesse.
Gorris Hans-Heiner
Rissin David M.
Walt David R.
Cassan Maclean
Trustees Of Tufts College
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