Methods and biomarkers for diagnosing and monitoring...

Details Methods and biomarkers for diagnosing and monitoring... Methods and biomarkers for diagnosing and monitoring...

G - Physics

01

N

G01N 33/68 (2006.01) A61K 39/395 (2006.01) C07K 16/00 (2006.01)

Patent

CA 2676091

A method of diagnosing or monitoring a psychotic disorder, or predisposition thereto, comprises measuring, in a sample taken from a subject, the level of a biomarker selected from clusterin precursor, inter .alpha.-trypsin inhibitor, IgM, apolipoprotein A2 and .alpha.2 H5 glycoprotein.

La présente invention concerne un procédé permettant de diagnostiquer ou de surveiller un trouble psychotique ou une prédisposition à tel trouble. Ce procédé consiste à mesurer dans un échantillon prélevé sur une personne la concentration d'un biomarqueur choisi parmi un précurseur de clustérine, un inhibiteur d'inter .alpha.-trypsine, IgM, une apolipoprotéine A2 et une glycoprotéine .alpha.2 H5.

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