A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/21 (2006.01) A61K 31/04 (2006.01) A61K 45/06 (2006.01) A61P 9/00 (2006.01) A61P 9/12 (2006.01)
Patent
CA 2478089
Therapies are for treating patients in need of nitroglycerin therapy and allow increased dosage, postponement of tolerance and preconditioning, without exacerbating or causing hypotension. Methods for determining cross-tolerance, nitroglycerin effectiveness and dose are also disclosed. Composition for intravenous administration of nitroglycerin does not contain ethanol or contains less ethanol than conventional conpositions.
L'invention concerne des thérapies destinées à traiter des patients nécessitant un traitement à la nitroglycérine et permettant d'augmenter le dosage, de retarder la tolérance et de réaliser un préconditionnement sans accentuer ou provoquer une hypotension. L'invention concerne également des méthodes destinées à déterminer une tolérance croisée, l'efficacité de la nitroglycérine et une dose. Cette composition destinée à une administration de nitroglycérine par voie intraveineuse ne contient pas d'éthanol ou contient moins d'éthanol que les compositions classiques.
Chen Zhiqiang
Stamler Jonathan S.
Duke University
Ridout & Maybee Llp
LandOfFree
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