C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/53 (2006.01) C12N 5/10 (2006.01) C12N 9/02 (2006.01) C12N 9/06 (2006.01) C12Q 1/26 (2006.01) G01N 33/53 (2006.01)
Patent
CA 2430987
A cDNA encoding a novel human stearoy-CoA desaturase (dubbed "hSCD5") as well as vectors and cells comprising such polynucleotide are disclosed. Also described are assay methods for determining the ability of small molecules and other chemical agents to increase or decrease he enzymatic activity and/or gene expression level of hSCD5 as well as processes for using such agents to treat, prevent or diagnose a variety of diseases and other conditions.
La présente invention concerne un ADNc codant pour une nouvelle stéaryle CoA désaturase humaine (plus brièvement dénommée <=hSCD5>=) ainsi que des vecteurs et des cellules comprenant ces polynucléotides. Cette invention concerne aussi des techniques de dosage permettant de déterminer la capacité de petites molécules et d'autres agents chimiques d'augmenter l'activité enzymatique et/ou le niveau d'expression génique de hSCD5, ainsi que des processus d'utilisation de ces agents de façon à traiter, prévenir ou diagnostiquer diverses maladies et d'autres pathologies.
Mbm Intellectual Property Law Llp
Xenon Genetics Inc.
Xenon Pharmaceuticals Inc.
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