Methods and compositions for altering cell function

Details Methods and compositions for altering cell function Methods and compositions for altering cell function

A - Human Necessities

61

K

A61K 33/04 (2006.01)

Patent

CA 2650309

The present invention relates to compositions and methods for altering cell function. In particular, the present invention provides compositions comprising selenium (e.g., SEL- PLEX) and methods of using the same (e.g., as a therapeutic and/or prophylactic treatment). Additionally, the present invention demonstrates that specific forms of selenium (e.g., SEL-PLEX), when administered to a subject, possess the ability to alter (e.g., reduce) gene expression in various tissues (e.g., compared to expression in subjects not administered selenium).

La présente invention concerne des compositions et des procédés permettant de modifier la fonction cellulaire. En particulier, la présente invention concerne des compositions comprenant du sélénium (par exemple le SEL-PLEX) ainsi que des procédés pour l'utiliser (par exemple comme traitement thérapeutique et/ou prophylactique). En outre, la présente invention démontre que des formes spécifiques du sélénium (par exemple le SEL-PLEX), lorsqu'elles sont administrées à un sujet, sont capables de modifier (par exemple réduire) l'expression d'un gène dans divers tissus (par exemple comparée à l'expression chez des sujets qui n'ont pas reçu de sélénium).

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