Methods and compositions for ameliorating the undesirable...

A - Human Necessities – 61 – K

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A61K 31/519 (2006.01) A61K 31/41 (2006.01) A61P 39/00 (2006.01)

Patent

CA 2466869

In one aspect, the present invention provides chemoprotectant compositions that each comprise at least two of the chemoprotectants disclosed herein. The chemoprotectant compositions of the invention are useful, for example, for ameliorating at least one adverse effect of chemotherapy. In another aspect, the present invention provides methods of ameliorating at least one adverse effect of chemotherapy, the methods each comprising the step of administering to a subject undergoing chemotherapy an amount of a chemoprotectant composition that is effective to ameliorate at least one adverse effect of the chemotherapy.

Dans un mode de réalisation, la présente invention concerne des compositions de chimioprotecteurs qui comprennent chacune au moins deux des chimioprotecteurs selon l'invention. Les compositions chimioprotectrices selon l'invention sont utiles, par exemple, pour diminuer au moins un effet indésirable de la chimiothérapie. Dans un autre mode de réalisation, la présente invention concerne des méthodes permettant de diminuer au moins un effet indésirable de la chimiothérapie, lesdites méthodes consistant chacune à administrer à un patient subissant une chimiothérapie une quantité d'une composition chimioprotectrice qui est efficace pour diminuer au moins un effet indésirable de la chimiothérapie.

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