Methods and compositions for assessment of pulmonary...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01)

Patent

CA 2666584

The present invention provides methods for the assessment of risk of developing lung cancer in smokers and non-smokers using analysis of genetic polymorphisms. The present invention also relates to the use of genetic polymorphisms in assessing a subject's risk of developing lung cancer, and the suitability of a subject for an intervention in respect of lung cancer. Nucleotide probes and primers, kits, and microarrays suitable for such assessment are also provided.

La présente invention concerne des procédés destinés à la vérification du risque de développer un cancer du poumon chez des fumeurs et des non fumeurs par analyse des polymorphismes génétiques. L'invention concerne également l'utilisation de polymorphismes génétiques pour la vérification du risque d'un sujet de développer un cancer du poumon, et l'aptitude d'un sujet à subir une intervention par rapport au cancer du poumon. L'invention concerne aussi des sondes et des amorces, des nécessaires et des microréseaux convenant pour une telle vérification.

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