Methods and compositions for cancer prognosis

Details Methods and compositions for cancer prognosis Methods and compositions for cancer prognosis

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01)

Patent

CA 2749322

The invention provides methods to determine the cancer prognosis of subjects and to adapt the treatment protocol of subjects having or susceptible to cancer. The method comprised steps of determining in vitro the genotype of said subject at a polymorphism in the C3-ITGAM axis, making a cancer prognosis of the subject based on said genotype and selecting an anti-cancer treatment for the subject.

La présente invention concerne des méthodes permettant d'établir un pronostic de cancer chez des patients et d'adapter le protocole de traitement de patients atteints ou susceptibles d'être atteints d'un cancer. La méthode comprend les étapes consistant à déterminer in vitro le génotype dudit patient au niveau d'un polymorphisme dans l'axe C3-ITGAM, à établir un pronostic de cancer du patient sur la base dudit génotype et à sélectionner un traitement anticancéreux pour le patient.

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