Methods and compositions for combination rnai therapeutics

C - Chemistry – Metallurgy – 07 – H

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C07H 21/02 (2006.01) A01N 43/04 (2006.01) C07H 21/04 (2006.01) C12P 19/34 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2555531

Compositions and methods containing mixtures of siRNA molecules that target genes associated with disease are provided. The mixtures of siRNA molecules provide greater efficacy in reducing expression of disease-associated genes than individual siRNA molecules.

Des compositions et des procédés contenant des mélanges de molécules ARNsi ciblant les gènes associés à une maladie. Les mélanges de molécules d'ARNsi garantissent une meilleure efficacité dans la réduction de l'expression de gènes associés à une maladie que pour des molécules individuelles d'ARNsi.

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