A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/00 (2006.01) A61K 38/26 (2006.01) A61K 38/28 (2006.01) A61K 38/51 (2006.01)
Patent
CA 2160543
The subject invention concerns compositions and methods useful for the prevention or amelioration of autoimmune diseases. Specifically exemplified are compositions and methods useful in immunizing to delay or prevent insulin dependent diabetes. In a preferred embodiment, diabetes is prevented or delayed by the parenteral administration of a composition comprising specific antigenic peptides of B-chain insulin and further comprising incomplete Freund's adjuvant. The specifically exemplified insulin B-chain composition stimulates the immune response, and depresses the synthesis of cytotoxic lymphokines in the target tissue.
Maclaren Noel K.
Muir Andrew
Mbm & Co.
The University Of Florida Research Foundation
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