A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/72 (2006.01) A61K 47/42 (2006.01) A61P 11/00 (2006.01)
Patent
CA 2744940
The disclosure provides a drug composition formulated for inhalation comprising a conjugate of a surface active agent and a pulmonary active drug. The surface active agent has an affinity for the human alveolar/gas interface and comprises at least a portion of a mammalian lung surfactant of a mimic thereof. The disclosure also provides a method of treating a subject suffering from or at risk of suffering from a lung disease comprising administering to the subject a conjugate comprising a drug for lung treatment and a surface active agent by inhalation in an amount effective to induce a drug effect in the lungs.
La présente invention concerne une composition médicamenteuse à inhaler qui comprend un conjugué d'un agent de surface et d'un médicament pulmonaire actif. L'agent de surface possède une affinité pour l'interface alvéolaire humaine et comprend au moins une partie d'un tensioactif pulmonaire de mammifère ou une imitation de celui-ci. L'invention concerne également un procédé de traitement d'un sujet souffrant ou risquant de souffrir d'une maladie pulmonaire qui consiste à lui administrer par inhalation un conjugué comprenant un médicament pour le traitement des poumons et un agent de surface dans une quantité efficace pour induire un effet du médicament sur les poumons.
Guarnieri Frank
Paka Pulmonary Pharmaceuticals Inc.
Riches Mckenzie & Herbert Llp
LandOfFree
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