Methods and compositions for deterring abuse of orally...

Details Methods and compositions for deterring abuse of orally... Methods and compositions for deterring abuse of orally...

A - Human Necessities

61

K

A61K 9/44 (2006.01)

Patent

CA 2588725

This invention relates to an abuse deterrent formulation of an oral dosage form of a therapeutically effective amount of any active drug substance that can be subject to abuse combined with a gel forming polymer, a nasal mucosal irritating surfactant and a flushing agent. Such a dosage form is intended to deter abuse of the active drug substance via injection, nasal inhalation or consumption of quantities of the dosage unit exceeding the usual therapeutically effective dose.

L'invention concerne une formulation qui décourage l'abus d'une forme posologique orale d'une quantité efficace sur le plan thérapeutique de n'importe quelle substance médicamenteuse active pouvant être sujette à l'abus lorsqu'elle est combinée à un polymère gélifiant, un tensioactif irritant les muqueuses et un agent de rinçage. Une telle forme posologique est censée décourager l'abus de cette substance médicamenteuse active par injection, inhalation nasale ou consommation de quantités d'unités posologiques excédant la dose efficace sur le plan thérapeutique habituelle.

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