Methods and compositions for diagnosing and monitoring...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01) C40B 30/04 (2006.01) C07H 21/00 (2006.01)

Patent

CA 2483481

Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.

L'invention concerne des méthodes permettant de diagnostiquer ou de surveiller le rejet d'un greffon, en particulier le rejet d'un greffon cardiaque, chez un patient par la détection du niveau d'expression d'un ou de plusieurs gènes chez ce patient. Ladite invention concerne également des oligonucléotides de diagnostic servant à diagnostiquer ou à surveiller le rejet d'un greffon, en particulier le rejet d'un greffon cardiaque, ainsi que des trousses ou systèmes contenant lesdits oligonucléotides.

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