Methods and compositions for diagnosing and treating...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/00 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 5/10 (2006.01) C12N 15/12 (2006.01) C12N 15/63 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2417703

The present invention relates to the mammalian HKNG1, GNKH and TS genes, genes associated with bipolar affective disorder (BAD) in humans. The invention relates, in particular, to methods for the diagnostic evaluation, genetic testing and prognosis of HKNG1, GNKH, and TS neuropsychiatric disorders including schizophrenia, attention deficit disorder, a schizoaffective disorder, a bipolar affective disorder or a unipolar affective disorder.

La présente invention concerne les gènes mammifères HKNG1, GNKH et TS, associés à la maladie affective bipolaire chez les humains. Plus précisément, l'invention concerne des méthodes d'évaluation diagnostique, de dépistage génétique et de pronostic des troubles neuropsychiatriques liés aux gènes HKNG1, GNKH, et TS, notamment la schizophrénie, le trouble déficitaire de l'attention, le trouble schizo-affectif, la maladie affective bipolaire ou la maladie affective unipolaire.

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