Methods and compositions for diagnosing disease

Details Methods and compositions for diagnosing disease Methods and compositions for diagnosing disease

C - Chemistry, Metallurgy

12

N

C12N 15/85 (2006.01) C12N 15/113 (2010.01) A61K 48/00 (2006.01) C12N 15/12 (2006.01) C12N 15/63 (2006.01) C12Q 1/00 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2698212

The present invention relates to methods and compositions for diagnosing a disease or disorder in a subject by introducing into cells of the subject a diagnostic gene switch construct and monitoring expression of a reporter gene. The invention further relates to methods and compositions for monitoring the progression of a disease or disorder or the effectiveness of a treatment for a disease or disorder.

L'invention concerne des procédés et des compositions de diagnostic d'une maladie ou de troubles en introduisant dans des cellules du sujet une structure à commutation génique de diagnostic et en surveillant l'expression d'un gène rapporteur. L'invention concerne en outre des procédés et des compositions pour surveiller la progression d'une maladie ou de troubles, ou l'efficacité d'un traitement pour une maladie ou des troubles.

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