G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/48 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2742113
The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using assays that detect one or more markers selected from the group consisting of Clusterin, Heart- type fatty acid binding protein, Hepatocyte growth factor, Interferon gamma, Interleukin- 12 subunit beta, Interleukin-16, Interleukin-2, 72 kDa type IV collagenase, Matrix metalloproteinase-9, Midkine, and Serum amyloid P-component as diagnostic and prognostic biomarkers in renal injuries.
La présente invention concerne des procédés et des compositions permettant le suivi, le diagnostic et le pronostic, et la détermination de régimes de traitement chez des sujets souffrant ou soupçonnés d'être atteints d'une lésion rénale. En particulier, l'invention concerne l'utilisation de tests qui détectent un ou plusieurs marqueurs choisis dans l'ensemble consistant en clusterine, protéine de liaison des acides gras de type cardiaque, facteur de croissance des hépatocytes, interféron gamma, interleukine-12 sous-unité bêta, interleukine-16, interleukine-2, collagénase de type IV de 72 kDa, métalloprotéinase-9 de matrice, midkine, composant amyloïde P sérique, comme marqueurs biologiques diagnostiques et pronostiques en cas de lésions rénales.
Anderberg Joseph
Gray Jeff
Mcpherson Paul
Nakamura Kevin
Astute Medical Inc.
Perley-Robertson Hill & Mcdougall Llp
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