A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/18 (2006.01) A61K 31/00 (2006.01) A61K 35/12 (2006.01) A61K 38/00 (2006.01) A61P 21/00 (2006.01) A61P 25/00 (2006.01) C12N 5/06 (2006.01) C12N 5/08 (2006.01)
Patent
CA 2550383
Method for modulating the migration of neural progenitor cells in a mammal by exposing the cells to a VEGFR-2 ligand and FGF-2. Methods of treating neurological disorders by exposing the mammal to a VEGFR-2 ligand in the presence of FGF-2 are also provided. A composition including a biocompatible matrix associated with FGF-2 is also provided.
Cette invention concerne un procédé permettant de moduler la migration de cellules précurseurs neuronales chez un mammifère en exposant les cellules à un ligand VEGFR-2 et à FGF-2. Cette invention concerne également des méthodes de traitement de troubles neurologiques consistant à exposer le mammifère à un ligand VEGFR-2 en présence de FGF-2. Cette invention concerne en outre une composition comprenant une matrice biocompatible associée à FGF-2.
Kiss Jozsef Zoltan
Pepper Michael
Vutskits Laszlo
Zhang Huanxiang
Gowling Lafleur Henderson Llp
Imclone Systems Incorporated
Kiss Jozsef Zoltan
Pepper Michael
University Of Geneva
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