A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) A61K 9/127 (2006.01) A61K 31/7115 (2006.01) A61K 31/712 (2006.01) A61K 38/00 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2542099
Cationic liposomes with immunostimulatory nucleic acids are shown to stimulate the innate immune response, and synergistic combinations of such liposomal nucleic acids and therapeutic antibodies are provided to dramatically improve antibody dependent cellular cytotoxicity and target cell lysis.
Il a été démontré que les liposomes cationiques comportant des acides nucléiques immunostimulants stimulent la réponse immunitaire innée. Des combinaisons synergiques de ces acides nucléiques liposomaux et d'anticorps thérapeutiques sont utilisées pour renforcer considérablement la cytotoxicité cellulaire dépendant des anticorps et la lyse de cellules cibles.
Brodsky Irina
Chikh Ghania
Raney Sameersingh G.
Sekirov Laura
Tam Ying K.
Inex Pharmaceuticals Corporation
Smart & Biggar
Tekmira Pharmaceuticals Corporation
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