C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C07H 21/02 (2006.01) C07H 21/04 (2006.01) C12N 15/63 (2006.01) C12N 15/88 (2006.01) C12P 19/34 (2006.01)
Patent
CA 2527958
The present invention provides methods of enhancing the efficacy and specificity of RNAi. The invention also provides compositions for mediating RNAi. In particular, the invention provides siRNAs, shRNAs, vectors and transgenes having improved specificity and efficacy in mediating silencing of a target gene. Therapeutic methods are also featured.
L'invention concerne des méthodes permettant d'améliorer l'efficacité et la spécificité d'une interférence d'ARN (ARNi). L'invention concerne également des compositions destinées à médier une interférence d'ARN. L'invention concerne, en particulier, des ARNsi, des ARNsh, des vecteurs et des transgènes à spécificité et efficacité améliorées induisant l'extinction d'un gène ciblé.
Hutvagner Gyorgy
Schwarz Dianne
Simard Martin
Zamore Phillip D.
Borden Ladner Gervais Llp
University Of Massachusetts
LandOfFree
Methods and compositions for enhancing the efficacy and... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods and compositions for enhancing the efficacy and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods and compositions for enhancing the efficacy and... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1738685