Methods and compositions for evaluating genetic markers

Details Methods and compositions for evaluating genetic markers Methods and compositions for evaluating genetic markers

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C40B 30/04 (2006.01)

Patent

CA 2760439

Aspects of the invention relates to methods and compositions that are useful to reduce bias and increase the reproducibility of multiplex analysis of genetic loci. In some configurations, predetermined preparative steps and/or nucleic acid sequence analysis techniques are used in multiplex analyses for a plurality of genetic loci in a plurality of samples.

Selon l'invention, des aspects de celle-ci concernent des procédés et des compositions qui sont utiles pour réduire les partialités et pour augmenter la reproductibilité d'une analyse multiplex de loci génétiques. Dans certains configurations, des étapes de préparation prédéterminées et/ou des techniques d'analyse de séquence d'acide nucléique sont utilisées dans des analyses multiplex pour une pluralité de loci génétiques dans une pluralité d'échantillons.

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