Methods and compositions for fine lines and/or wrinkles

A - Human Necessities – 61 – K

Patent

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A61K 47/00 (2006.01)

Patent

CA 2243394

The invention provides methods and compositions for improving and reducing age-related skin disorders, particularly fine lines and/or wrinkles, including fine wrinkles, on human skin. The cosmetic compositions of the invention are formulated with less than effective amounts of anti-wrinkle activeagents (e.g., drugs) or are devoid of such active agents, which include .alpha.-hydroxy acid and derivatives and salts thereof, tretinoin and derivatives and salts thereof, or vitamin C, and which are typically used for treating and reducing skin lines and/or wrinkles. As tested in clinical trials, the compositions of the invention reduced and improved fine lines and/or wrinkles as well as, or better than, preparations containing .alpha.-hydroxy acids, .alpha.-hydroxy acid salts, tretinoin, or vitamin C, thereby achieving effective anti-wrinkle formulations that are safe, economical and stable, without potential adverse effects to the user that can accompany the use of the aforementioned, typically-employed antiwrinkle preparations and products.

L'invention porte sur des méthodes et des compositions pour corriger et atténuer les problèmes de peau liés à l'âge, notamment les fins sillons et (ou) les rides, incluant les fines rides, de la peau humaine. Les compositions cosmétiques de l'invention sont formulées avec des charges inférieures aux quantités efficaces d'agents anti-rides (p. ex. sous forme de médicaments), ou sont dépourvues de ces agents; parmi ces derniers, on peut citer les acides alpha-hydroxylés ainsi que leurs dérivés et sels, la trétinoïne ainsi que ses dérivés et sels et la vitamine C, qui sont habituellement employés pour traiter et corriger les sillons et (ou) les rides de la peau. Comme l'ont montré les essais cliniques, les compositions de l'invention ont réduit et corrigé les sillons fins et (ou) les rides aussi bien et même mieux que les préparations renfermant des acides alpha-hydroxylés, des sels d'acides alpha-hydroxylés ou la vitamine C; on a ainsi obtenu des formulations anti-rides efficaces, sûres, économiques et stables, sans risque d'effets nocifs pour l'utilisateur, comme ceux qui peuvent résulter de l'emploi des produits et préparations anti-rides susmentionnés, couramment utilisés.

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