Methods and compositions for gene therapy

Details Methods and compositions for gene therapy Methods and compositions for gene therapy

A - Human Necessities

61

K

A61K 47/48 (2006.01) A61K 48/00 (2006.01) C12N 15/861 (2006.01)

Patent

CA 2663854

The present invention relates to improved methods for gene therapy, particularly gene therapy using PEGylated adenovirus. In particular the invention provides methods and compositions for mitigating the adverse effects associated with systemic administration of recombinant adenovirus for gene therapy.

La présente invention concerne des procédés améliorés pour une thérapie génique, en particulier une thérapie génique utilisant des adénovirus pégylés. L'invention fournit, en particulier, des procédés et des compositions pour atténuer les effets indésirables associés à une administration systémique d'adénovirus recombinés pour une thérapie génique.

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