G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/573 (2006.01) G01N 33/574 (2006.01)
Patent
CA 2426517
The present invention is directed to compositions and methods for measuring enzymatic activity, particularly glycosidase activity. Methods of the present invention include assays for quantitatively determining the amount of glycosidase activity in a sample. The present invention also provides methods for the diagnosis of metastatic and inflammatory processes in vitro and in vivo. The present invention further provides compositions and methods for high throughput assays for identifying compounds that effect glycosidase activity.
La présente invention concerne des compositions et des procédés qui permettent de mesurer l'activité enzymatique, notamment l'activité glycosidase. Les procédés selon l'invention comprennent des dosages permettant de déterminer quantitativement l'activité glycosidase dans un échantillon. Cette invention concerne également des procédés de diagnostic des processus métastatiques et inflammatoires <i>in vitro</i> et <i>in vivo</i>, ainsi que des compositions et des procédés de dosage à rendement élevé permettant d'identifier des composés qui inhibent l'activité glycosidase.
Pillarisetti Sivaram
Saxena Uday
Wang Dongyan
Finlayson & Singlehurst
Pillarisetti Sivaram
Reddy Us Therapeutics Inc.
Saxena Uday
Wang Dongyan
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