Methods and compositions for identifying therapeutic compounds

Details Methods and compositions for identifying therapeutic compounds Methods and compositions for identifying therapeutic compounds

C - Chemistry, Metallurgy

12

Q

C12Q 1/44 (2006.01)

Patent

CA 2543142

By the present invention, enzymes responsible for prodrug activation are identified and utilized for the identification of candidate compounds as prodrugs. The present invention includes methods for identifying a candidate compound as a suitable prodrug as well as methods of screening candidate compounds for suitability as therapeutic agents.

Selon l'invention, des enzymes responsables de l'activation de promédicaments sont identifiées et utilisées pour identifier des composés candidats en tant que promédicaments. L'invention concerne notamment des procédés permettant d'identifier un composé candidat en tant que promédicament adapté, ainsi que des procédés de criblage de composés candidats susceptibles de constituer des agents thérapeutiques adaptés.

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