Methods and compositions for increased dynamic range...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01)

Patent

CA 2595729

The present invention provides systems, methods and kits for increasing the dynamic range of detection of a target nucleic acid in a sample. In particular, the present invention provides methods and kits for increasing the dynamic range of detection of a target nucleic acid in a sample through the use of one or more probe oligonucleotides (e.g., analyte-specific probe oligonucleotides).

Cette invention concerne des systèmes, des méthodes et des trousses permettant d'augmenter la plage dynamique de détection d'un acide nucléique cible dans un échantillon. Plus particulièrement, cette invention concerne des méthodes et des trousses permettant d'augmenter la plage dynamique de détection d'un acide nucléique cible dans un échantillon grâce à l'utilisation d'un ou de plusieurs oligonucléotides sondes (par exemple, des oligonucléotides sondes propres aux analytes).

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