A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 45/08 (2006.01) A01N 25/00 (2006.01) A01N 37/00 (2006.01) A01N 37/18 (2006.01) A01N 47/34 (2006.01) A01N 61/00 (2006.01) A01N 63/00 (2006.01) A61K 47/46 (2006.01) A61P 35/00 (2006.01) C12N 7/00 (2006.01)
Patent
CA 2502148
The invention provides methods and compositions for modulating the sensitivity of cells to cytotoxic compounds and other active agents. In accordance with the invention, compositions are provided comprising combinations of ectophosphatase inhibitors and active agents. Active agents include antibiotics, fungicides, herbicides, insecticides, chemotherapeutic agents, and plant growth regulators. By increasing the efficacy of active agents, the invention allows use of compositions with lowered concentrations of active ingredients.
La présente invention concerne des procédés et des compositions pour moduler la sensibilité de cellules à des composés cytotoxiques et d'autres substances actives. L'invention a pour objet des compositions comprenant des combinaisons d'inhibiteurs d'ectophosphatase et de substances actives. Les substances actives comprennent des antibiotiques, des fongicides, des herbicides, des insecticides, des agents de chimiothérapie, et des régulateurs de croissance végétale. Grâce à l'augmentation de l'efficacité des substances actives, l'invention permet l'utilisation de compositions ayant des concentrations plus faibles en substances actives.
Lloyd Alan M.
Roux Stan J.
Thomas Collin E.
Windsor J. Brian
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Board Of Regents The University Of Texas System
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