Methods and compositions for inhibiting c-met dimerization...

Details Methods and compositions for inhibiting c-met dimerization... Methods and compositions for inhibiting c-met dimerization...

C - Chemistry, Metallurgy

07

K

C07K 16/18 (2006.01) A61K 38/03 (2006.01)

Patent

CA 2548282

The invention provides methods and compositions for modulating the HGF/c-met signaling pathway, in particular by regulating c-met dimerization and/or binding of ligand to c-met using a c-met antagonist that disrupts c-met multimerization.

L'invention concerne des méthodes et des compositions pour moduler la voie de signalisation de HGF/c-met, en particulier par la régulation de la dimérisation de c-met et/ou par une liaison de ligand à c-met, au moyen d'un antagoniste de c-met perturbant la multimérisation de c-met.

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